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[(Am)18.7(on)20.8(g)-329.4(1)0(0)20.8(0)-329.4(pa)19.7(rt)20.7(ic)13.8(ip)20.7(an)19.7(ts)20.9(,)-331.7(2)0(5)20.8(%)-324.7(we)13(re)-314.3(fe)14(ma)18.4(le)19.6(,)-326(t)0(h)20.7(e)-330.6(me)18.4(an)-320.1(ag)19.7(e)]TJ
-1.0137 -1.1116 TD
[(wa)18.8(s)-450.2(4)0(5)-439.9(\()0(S)21(D)-451.2(12)20.8(\),)-442.2(63)20.8(%)-445.7(w)0(e)18.8(r)0(e)-441.1(A)0(f)20(r)0(i)15(c)0(a)18.5(n)-444.6(Am)18.7(er)14(ic)19.6(an)19.7(,)-446.9(2)0(7)20.8(%)-451.4(we)18.8(re)]TJ
T*
[(pu)15.1(bl)20.7(ic)19.5(ly)-503.4(in)20.7(su)15.3(re)19.7(d,)-505.6(41)20.8(%)-514.8(w)0(e)18.8(r)0(e)-504.4(u)0(n)15.1(i)0(n)20.7(s)0(u)21(r)0(e)19.7(d)0(,)-505.6(t)0(h)20.7(e)-520.6(m)15(e)0(d)13.9(i)0(a)19.6(n)-513.7(CD)18.9(4)]TJ
/F5 1 Tf
7.3823 0 0 6.5614 294.9731 137.707 Tm
(+)Tj
/F4 1 Tf
9.843 0 0 9.843 59.7543 122.3999 Tm
[(T)-221.2(c)0(e)18.5(l)0(l)-209.8(c)0(o)19.7(u)0(n)20.8(t)-220.1(wa)18.8(s)-219.8(5)0(7)20.8(2)-220(ce)18.5(ll)14.8(s/)20.9(mm)]TJ
7.3823 0 0 6.5614 177.3921 126.7653 Tm
(3)Tj
9.843 0 0 9.843 183.2314 122.3999 Tm
[(\(i)20.7(nt)20.7(er)19.7(qu)15.1(ar)19.7(ti)20.6(le)-210.8(ra)19.7(ng)20.8(e)-221.1(3)0(0)20.8(7)0()20.8(7)0(8)20.8(8)0(\))20.9(,)]TJ
-12.5446 -1.1174 TD
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0 -1.1116 TD
[(30)-272.9(ha)19.7(d)-283.3(c)0(h)19.7(r)0(o)20.9(n)0(i)14.9(c)-278.7(pa)19.7(in)-273(ba)19.7(se)19.9(d)-283.3(o)0(n)-272.9(t)0(h)20.7(e)-284.5(BC)18.8(PQ)20.1(.)-279.9(O)0(f)-273.7(i)0(n)20.7(d)0(i)15(v)0(i)20.7(d)0(u)20.8(a)0(l)19.6(s)-283.1(wi)19.8(th)]TJ
T*
[(ch)19.7(ro)15.1(ni)20.7(c)-169.3(p)0(a)13.9(i)0(n)20.7(,)-170.5(th)20.7(re)19.7(e)-175(\()0(1)20.9(0)0(%)19.8(\))-173.9(re)19.7(po)20.8(rt)20.7(ed)-164.6(mi)19.5(ld)-163.6(ch)19.7(ro)20.9(ni)20.7(c)-175(p)0(a)19.7(i)0(n)20.7(,)-170.5(19)-163.5(\(6)20.9(3%)19.8(\))]TJ
0 -1.1174 TD
[(mo)19.6(de)19.7(ra)14(te)19.5(,)-308.7(s)0(i)20.9(x)-312.1(\(2)20.9(0%)19.8(\))-312.1(s)0(e)19.9(v)0(e)19.7(r)0(e)19.7(,)-308.7(an)13.9(d)-306.4(t)0(w)19.8(o)-312.1(\(7)20.9(%\))-302.7(ve)19.7(ry)-301.7(se)19.9(ve)19.7(re)19.7(.)-308.7(A)0(s)-302.4(a)]TJ
0 -1.1116 TD
[(ch)19.7(ec)12.8(k)-323.6(o)0(f)-318.9(i)0(n)20.7(t)0(e)19.6(r)0(n)15.1(a)0(l)-314.5(c)0(o)13.9(n)0(s)21(i)0(s)20.9(t)0(e)19.6(n)0(c)19.7(y)0(,)-321.3(n)0(o)-313.2(p)0(a)13.9(r)0(t)20.7(i)0(c)19.6(i)0(p)20.7(a)0(n)19.7(t)0(s)-318.9(i)0(n)-319.1(t)0(h)20.7(e)-330.6(pa)19.7(in)-319.1(se)19.9(-)]TJ
T*
[(ve)19.7(ri)15(ty)-163.6()62.3()0(n)20.9(o)0(n)20.8(e)0()65.8()-173.9(gr)20.9(ou)20.8(p)-173.9(r)0(e)19.7(p)0(o)15.1(r)0(t)20.7(e)0(d)-164.6(h)0(a)19.7(v)0(i)20.7(n)0(g)-163.5(p)0(a)19.7(i)0(n)-163.6(i)0(n)-169.4(t)0(h)20.7(e)-175(pa)19.7(st)-163.4(3)-173.9(m)0(o)19.6(n)0(t)20.7(h)0(s)15.3(.)]TJ
26.5234 34.5122 TD
-.0159 Tc
[(In)-201.3(the)-202.5(c)-.9(ro)-15.9(s)10.9(s).5(-s)-15.9(e)9.7(c)-.9(tio)-15.9(n)10.7(a)-.9(l)-201.4(a)-.9(nal)-15.9(y)10.6(sis)-15.9(,)-187.3(par)-15.9(t)10.6(icip)-15.9(a)9.5(n).3(ts)-201.1(wi)-15.9(t)10.4(h)-201.3(chro)-15.9(n)10.7(i).1(c)-202.5(p).3(ain)]TJ
-1.0137 -1.1116 TD
-.0158 Tc
[(were)-213.9(more)-213.9(li)-15.8(k)10.7(e)-.8(ly)-212.7(than)-212.7(par)-15.8(t)10.7(icip)-15.8(a)9.6(n).4(ts)-212.5(wit)-15.8(h)10.7(out)-212.9(chr)-15.8(o)10.8(nic)-213.9(p).4(ain)-212.7(t).2(o)-212.7(h).4(av)-15.8(e)]TJ
T*
[(impai)-15.8(r)10.7(ed)-425.8(mobi)-15.8(l)10.5(i).3(ty)-425.8(\(4)-15.8(3)10.8(%)-426.9(vs.)-428.2(12%,)]TJ
/F6 1 Tf
14.0825 0 TD
0 Tc
(p)Tj
/F5 1 Tf
.6508 0 TD
(=)Tj
/F4 1 Tf
.7027 0 TD
-.0159 Tc
[(0.001\))-15.9(,)-412.1(d).3(i)-15.9(f)10.6(cul)-15.9(t)10.4(y)-425.9(with)]TJ
-15.436 -1.1174 TD
-.0161 Tc
[(usua)-16.1(l)-261.5(a)-16.1(c)8.2(tivit)-16.1(i)10.2(e)-1.1(s)-276.2(\(47%)-277.4(vs)-16.1(.)-262.3(12%,)]TJ
/F6 1 Tf
12.1127 0 TD
0 Tc
(p)Tj
/F5 1 Tf
.6508 0 TD
(<)Tj
/F4 1 Tf
.7027 0 TD
-.0158 Tc
[(0.001)-15.8(\))10.8(,)-272.7(lo)-15.8(w)9.9(e)-.8(r)-276(overa)-15.8(l)9.5(l)-276.2(health)]TJ
-13.4662 -1.1116 TD
-.0159 Tc
[(stat)-15.9(e)-163.4(\(70)-172.5(vs)-15.9(.)-158.5(8).3(4)-15.9(,)]TJ
/F6 1 Tf
6.0362 0 TD
0 Tc
(p)Tj
/F5 1 Tf
.6508 0 TD
(=)Tj
/F4 1 Tf
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-.016 Tc
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/F6 1 Tf
12.8038 0 TD
0 Tc
(p)Tj
/F5 1 Tf
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(<)Tj
/F4 1 Tf
.7027 0 TD
-.0157 Tc
[(0.001)-15.7(\))10.9(,)]TJ
-21.5471 -1.1116 TD
0 Tc
[(a)15(n)16.2(d)-266(a)15(nx)26.6(i)16.1(e)15(t)16.1(y)-266(\(4)26.6(3)16.2(%)-267.1(v)16.2(s)0(.)-252(1)16.2(0%)25.5(,)]TJ
/F6 1 Tf
10.8801 0 TD
(p)Tj
/F5 1 Tf
.6566 0 TD
(<)Tj
/F4 1 Tf
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-.0159 Tc
[(0.001\))-281.9(\()-15.9(T)9.5(able)-283.1(2)-15.9(\))10.7(.)-284.3(A)-.6(ddit)-15.9(i)10.4(onall)-15.9(y)10.6(,)]TJ
-12.2394 -1.1174 TD
-.0157 Tc
[(the)-294.4(P)-15.7(H)10.2(Q)-.4(-9)-299(thres)-15.7(h)11.1(old)-299(for)-293.2(d)-15.7(e)9.7(pres)-15.7(s)11.3(ion)-299(w)-.4(as)-293.1(mor)-15.7(e)-284(commo)-15.7(n)10.9(l).3(y)-293.3(met)]TJ
0 -1.1116 TD
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[(among)-420.2(par)-15.9(t)10.6(icipa)-15.9(n)9.5(ts)-420(with)-420.2(chr)-15.9(o)10.7(nic)-421.3(p).3(ain,)-422.5(altho)-15.9(u)10.7(gh)-420.2(this)-420(did)-420.2(not)]TJ
T*
-.0155 Tc
[(reach)-414(s)-15.5(t)11.2(atis)-15.5(t)11.2(i).5(cal)-414.1(s)-15.5(i)11.2(gni)-15.5(c)10.1(ance)-415.2(\(30)-15.5(%)-398.9(v)-15.5(s)11.3(.)-410.6(1)-15.5(5)11.1(%,)]TJ
/F6 1 Tf
18.0567 0 TD
0 Tc
(p)Tj
/F5 1 Tf
.6508 0 TD
(=)Tj
/F4 1 Tf
.7084 0 TD
-.0157 Tc
[(0.10\).)-416.5(Other)]TJ
-19.416 -1.1174 TD
-.0159 Tc
[(test)-15.9(s)-259.9(o).3(f)-270.4(a)-.9(ss)-15.9(o)10.9(c)-.9(iat)-15.9(i)10.4(on)-270.4(fel)-15.9(l)-260.3(consi)-15.9(d)10.6(erab)-15.9(l)10.6(y)-270.4(shor)-15.9(t)-260.1(o).3(f)-270.4(s).5(t)-15.9(a)9.4(tist)-15.9(i)10.4(cal)-270.6(si)-15.9(g)10.6(n).3(i-)]TJ
0 -1.1116 TD
-.0156 Tc
[(cance)-15.6(.)-453.3(T)-.6(h)-15.6(e)9.8(se)-467.1(in)-15.6(c)9.8(l).4(uded)-471.7(t).5(est)-15.6(s)-455.5(of)-465.9(as)-15.6(s)11.4(o).6(ci)-15.6(a)9.7(tion)-471.7(b).6(etwee)-15.6(n)-456.7(BCPQ-)]TJ
T*
-.0159 Tc
[(iden)-15.9(t)10.6(i).2(ed)-276.2(c)-.9(hron)-15.9(i)10.6(c)-271.6(pai)-15.9(n)-260.1(and)-276.2(a)-.9(dvanc)-15.9(e)8.4(d)-270.4(age)-277.3(\(49)-270.4(v)-15.9(s)10.9(.)-272.8(45,)]TJ
/F6 1 Tf
20.6773 0 TD
0 Tc
(p)Tj
/F5 1 Tf
.6508 0 TD
(=)Tj
/F4 1 Tf
.7027 0 TD
-.0156 Tc
[(0.23)-15.6(\))11(,)]TJ
-22.0309 -1.1116 TD
-.016 Tc
[(subs)-16(t)10.7(a)-1(nce)-490.6(u).2(s)-16(e)-479.9(\(7%)-490.5(vs.)-491.7(4).2(%,)]TJ
/F6 1 Tf
11.7383 0 TD
0 Tc
(p)Tj
/F5 1 Tf
.6508 0 TD
(=)Tj
/F4 1 Tf
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-.0158 Tc
[(0.64\),)-491.5(and)-489.2(s).6(u)-15.8(b)10.8(opti)-15.8(m)9.4(al)-489.3(anti-)]TJ
-13.0918 -1.1174 TD
[(retr)-15.8(o)10.8(v).4(ira)-15.8(l)-261.2(treat)-15.8(m)9.4(e)-.8(nt)-270.5(\(AR)-15.8(T)8.6(\))-270.3(a)-.8(dher)-15.8(e)9.7(nce)-271.5(\().4(3)-15.8(3)10.8(%)-271.4(v).4(s.)-272.7(26%,)]TJ
/F6 1 Tf
20.8904 0 TD
0 Tc
(p)Tj
/F5 1 Tf
.6508 0 TD
(=)Tj
/F4 1 Tf
.7027 0 TD
[(0.)30(6)16.2(\))0(.)]TJ
-21.2303 -1.1116 TD
[(Just)-205.7(42)-203.8(participants)-212.8(had)-211.8(two)-205.9(PROs)]TJ
/F5 1 Tf
13.9154 0 TD
(>)Tj
/F4 1 Tf
.72 0 TD
[(3)-208.4(months)-203.6(apart)-209.5(within)]TJ
-15.6491 -1.1116 TD
[(18)-393.9(months,)-391.4(and)-396.1(were)-393.5(therefore)-399.3(included)-397.3(in)-394(the)-396.2(analysis)-396.9(of)]TJ
0 -1.1174 TD
[(rep)12.9(ea)12.8(ted)-384.7(rep)12.8(ort)13.9(s)-392.6(o)0(f)-388.1(pai)12.7(n,)-390.4(de)13.9(pre)12.8(ssi)14.2(on,)-385.8(anx)12.8(iet)12.6(y,)-384.7(and)-384.6(imp)12.6(air)12.7(ed)]TJ
0 -1.1116 TD
[(mob)18.5(ili)13.6(ty/)13.7(usu)14.2(al)-291.5(act)11.5(ivi)13.7(tie)12.6(s.)-292.3(No)-291.1(sta)12.9(tis)13.9(tic)12.6(all)12.6(y)-294.8(sig)14(ni)14(can)11.7(t)-295(rel)12.7(at)13.8(ion)13.9(-)]TJ
T*
[(shi)14(ps)-382.1(we)13(re)-383.5(fou)14(nd)-382.3(in)-382.5(the)12.7(se)-377.5(ana)11.7(lys)14(es.)-381(Al)14.1(tho)13.9(ugh)-377.7(not)-377.8(att)12.6(ain)12.7(in)14.9(g)]TJ
0 -1.1174 TD
[(sta)12.9(tis)13.9(tic)12.6(al)-193.6(sig)14(ni)14(can)11.7(ce,)-198(the)-188.9(mos)12.9(t)-202.8(sug)14.2(ges)13(tiv)13.7(e)-203.8(rel)12.7(ati)12.6(ons)14.2(hip)13.9(s)-202.5(w)0(e)13(r)0(e)]TJ
0 -1.1116 TD
-.0159 Tc
[(betw)-15.9(e)8.7(e)-.9(n)-345.3(B)-.7(C)-15.9(P)9.8(Q-i)-15.9(d)10.6(enti)-15.9()10.7(e)-.9(d)-345.3(c)-15.9(h)9.5(ron)-15.9(i)10.6(c)-346.5(pai)-15.9(n)-335(and)-351.1(r).3(epo)-15.9(r)10.7(tin)-15.9(g)-334.9(t).2(he)-352.2(fol-)]TJ
T*
[(lowi)-15.9(n)10.6(g)-281.9(twic)-15.9(e)-273.9(i).2(n)-281.9(t).2(he)-283.1(pre)-15.9(c)8.4(e)-.9(din)-15.9(g)-271.5(18)-281.9(month)-15.9(s)10.9(:)-282.1(p).3(ai)-15.9(n)-271.7()52.2(t)-15.9(o)10.6(d).3(ay)46.4()-281.9(\(65)-15.9(%)]TJ
0 -1.1174 TD
0 Tc
[(v)16.2(s)16.4(.)-297.2(3)16.2(3%)25.5(,)]TJ
/F6 1 Tf
3.7323 0 TD
(p)Tj
/F5 1 Tf
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(=)Tj
/F4 1 Tf
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[(0.13\))-15.9(,)-296.9(i)-15.9(m)9.3(p).3(air)-15.9(e)9.6(d)-310.7(m)-.9(obi)-15.9(l)10.4(i).2(ty)-316.5(\(26%)-311.8(v)-15.9(s)10.9(.)-313.1(0).3(%,)]TJ
/F6 1 Tf
15.5858 0 TD
0 Tc
(p)Tj
/F5 1 Tf
.6508 0 TD
(=)Tj
/F4 1 Tf
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[(0.30)-15.6(\))11(,)]TJ
-22.0309 -1.1116 TD
[(and)-293.2(i).5(mpair)-15.6(e)9.9(d)-287.4(u)-15.6(s)11.2(u).6(al)-293.3(activ)-15.6(i)10.9(t).5(ie)-15.6(s)-278(\().6(3)-15.6(0)11(%)-288.5(v).6(s)-15.6(.)-279.1(0%,)]TJ
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17.1409 0 TD
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(p)Tj
/F5 1 Tf
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(=)Tj
/F4 1 Tf
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-.0155 Tc
[(0.15)-15.5(\))11.1(.)-289.6(No)-287.3(r)-15.5(e)10(la-)]TJ
-18.4944 -1.1116 TD
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[(tion)-15.8(s)11(hip)-230(w)-15.8(a)8.8(s)-229.8(obs)-15.8(e)9.8(rved)-230(b)-15.8(e)9.6(t).3(wee)-15.8(n)-215(t)-15.8(h)10.7(e)-231.2(BCPQ)-230.9(a)-.8(n)-15.8(d)-219.6(repea)-15.8(t)9.5(ed)-230(rep)-15.8(o)10.8(rts)]TJ
T*
0 Tc
[(o)16.2(f)-266(d)16.2(e)15(pr)26.6(e)15(s)16.4(si)26.7(o)16.2(n)-266(a)15(n)16.2(d)-266(a)15(nx)26.6(i)16.1(e)15(t)16.1(y)-266(\(T)25.4(a)15(b)16.2(l)16.1(e)-267.2(2)16.2(\))0(.)]TJ
/F1 1 Tf
8.9663 0 0 8.9663 310.8472 94.9606 Tm
(Discussion)Tj
/F4 1 Tf
9.843 0 0 9.843 320.8251 78.5197 Tm
[(This)-495.1(is)-503.2(the)-494.2(rst)-499.5(study)-500.8(to)-497.7(quantitatively)-503.5(investigate)-505.5(the)]TJ
-1.0137 -1.1116 TD
[(BCPQ)-468(in)-468.9(any)-471(clinical)-473.6(population,)-471(including)-466.5(HIV-infected)]TJ
T*
[(patients.)-193.3(Because,)-201(for)-193.3(example,)-194.6(many)-196.9(but)-193.5(not)]TJ
/F6 1 Tf
17.9357 0 TD
(all)Tj
/F4 1 Tf
1.2556 0 TD
[(patients)-195.6(with)]TJ
ET
59.754 719.716 490.167 .22681 re
f
59.754 602.249 490.167 .22681 re
f
59.754 700.724 490.167 .22675 re
f
59.754 602.419 490.167 .28345 re
f
59.754 524.863 490.167 .22681 re
f
59.754 583.483 490.167 .22681 re
f
BT
/F8 1 Tf
9.845 0 0 9.845 95.1307 725.3856 Tm
(Table)Tj
/F4 1 Tf
3.0002 0 TD
(2.)Tj
/F8 1 Tf
1.2496 0 TD
[(Relationship)-338.7(Between)-332.7(the)-338.1(Brief)-329.8(Chronic)-338.5(Pain)-333.2(Questionnaire)-339.5(and)-332(Other)-335.2(Variables)]TJ
/F6 1 Tf
-7.8431 -1.86 TD
[(Cross-sectional)-340.5(measures)-10848.1(Chronic)-337.3(pain)]TJ
/F4 1 Tf
7.3837 0 0 6.5625 321.9023 711.4392 Tm
(a)Tj
9.845 0 0 9.845 328.5353 707.0739 Tm
(N)Tj
/F5 1 Tf
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(=)Tj
/F6 1 Tf
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[(30)-3278.6(No)-331.2(chronic)-337.5(pain)]TJ
/F4 1 Tf
7.3837 0 0 6.5625 452.1259 711.4392 Tm
(a)Tj
9.845 0 0 9.845 458.7022 707.0739 Tm
(N)Tj
/F5 1 Tf
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(70)Tj
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4.2728 0 TD
(p)Tj
/F6 1 Tf
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(-value)Tj
/F4 1 Tf
7.3837 0 0 6.5625 546.2361 711.4392 Tm
(b)Tj
9.845 0 0 9.845 59.7543 688.2518 Tm
[(Age)-339(\(median,)-336.5(IQR\))-15392.6(49)-330.2(\(3955\))-8086.2(45)-330.2(\(3653\))-7015.1(0.23)]TJ
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[(Impaired)-339.8(usual)-334.4(activities)-13281.8(14)-330.2(\(47%\))-9254.2(8)-329.2(\(12%\))]TJ
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46.696 0 TD
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(0.001)Tj
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T*
[(Pain)-21542.1(24)-330.2(\(80%\))-8753.2(18)-330.2(\(27%\))]TJ
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[(Substance)-340.5(use)-18085.8(2)-335(\(7%\))-9754.2(3)-329.2(\(4%\))-8182.1(0.64)]TJ
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(c)Tj
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[(30)-4793.1(Acute)-336.9(pain)]TJ
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(N)Tj
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(a)Tj
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[(Pain)-21657.3(15)-330.2(\(65%\))-9046.9(3)-335(\(33%\))-7342.3(0.13)]TJ
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T*
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6.5633 0 0 5.8334 67.748 516.9258 Tm
(a)Tj
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[(3)-329.2(months.)]TJ
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(b)Tj
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(c)Tj
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[(Presence)-303.1(of)-307.2(positive)-303.9(result)-306(on)-302.2(measure)-307.3(\(e.g.,)-302.2()54.4(pain)-303.6(today)60.3(\))-305.8(over)-306(two)-302(points)-306.3(in)-300.9(time)-309(\(two)-299.4(measures)]TJ
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[(3)-303.3(months)-305.1(apart)-304.8(within)-302.4(18)-308.6(months)]TJ
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T*
[(suboptimal)-383.4(adherence,)-378.8(no)-379.9(chronic)-386.7(pain)-377.5(3;)-378.6(pain,)-380.1(chronic)-380.2(pain)-384(7;)-378.6(depression,)-382.6(chronic)-380.2(pain)-384(7;)-378.6(anxiety,)-376.6(chronic)-386.7(pain)-377.5(7;)-378.6(impaired)-381.8(mobility,)]TJ
T*
[(chronic)-393.2(pain)-390.4(7;)-398.1(impaired)-388.3(usual)-394.1(activities,)-394.7(chronic)-393.2(pain)-390.4(7;)-391.6(pain,)-393.1(acute)-391.6(pain)-390.4(3;)-391.6(depression,)-395.6(acute)-391.6(pain)-390.4(3;)-391.6(anxiety,)-396(acute)-391.6(pain)-390.4(4;)-391.6(impaired)]TJ
T*
[(mobility,)-335.7(acute)-333.3(pain)-332.1(4;)-333.3(impaired)-336.5(usual)-329.4(activities,)-336.4(acute)-333.3(pain)-332.1(3.)]TJ
/F1 1 Tf
8.9663 0 0 8.9663 59.7543 749.7069 Tm
[(INSTRUMENT)-339.7(TO)-337.5(IDENTIFY)-336(CHRONIC)-336.8(PAIN)-335.9(IN)-328.8(HIV)-28798.8(625)]TJ
ET
endstream
endobj
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9.843 0 0 9.843 62.022 725.1588 Tm
0 0 0 1 k
0 Tc
0 Tw
[(chronic)-430.6(pain)-426.2(have)-427.2(depression,)-431.2(we)-424.7(did)-429.6(not)-423.9(expect)-430.7(to)-422.8(see)-431.6(a)]TJ
0 -1.1174 TD
[(100%)-385.6(correlation)-390.3(between)-386.6(the)-384.7(BCPQ)-387.3(and)-384.6(the)-384.7(other)-386.9(instru-)]TJ
0 -1.1116 TD
[(ments)-324.6(investigated.)-325.7(Rather,)-324.5(in)-319.1(support)-324.4(of)-319(construct)-329.1(validity,)]TJ
T*
[(we)-344.1(looked)-342(for)-337.3(trends)-341.7(across)-342.6(instruments.)-346.2(For)-342.9(several)-339.4(of)-342(the)]TJ
T*
[(measures)-295.3(tested,)-294.7(the)-292.6(BCPQ)-295.2(correlated)-298.1(as)-291.2(hypothesized)-293.2(\(mo-)]TJ
0 -1.1174 TD
[(bility,)-436.8(problems)-443.1(with)-437.5(usual)-438.6(activities,)-444.6(overall)-436.5(health)-441.2(state,)]TJ
0 -1.1116 TD
[(pain)-311(tod)13.8(a)15(y)16.2(,)-297.2(a)15(nx)26.6(i)16.1(e)15(t)16.1(y)0(,)-281(d)16.2(ep)25.4(r)16.2(e)15(ss)27(i)16.1(o)16.2(n\))26.6(.)-297.2(S)16.3(o)16.2(m)15(e)-296(f)16.2(el)25.3(l)-295(s)16.4(h)16.2(o)0(r)26.6(t)-295(o)16.2(f)-294.8(st)26.7(a)15(t)16.1(is)26.7(t)16.1(i)16.1(c)0(a)24.3(l)]TJ
T*
-.0159 Tc
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T*
-.0156 Tc
[(vi)-15.6(o)10.9(u).6(sl)-15.6(y)-208(fou)-15.6(n)11(d)-218.3(an)-224(asso)-15.6(c)9.8(i).5(at)-15.6(i)10.7(o).6(n)-218.3(b)-15.6(e)9.8(t).5(wee)-15.6(n)-209(pai)-15.6(n)-208(and)-224(A)-.3(RT)-219.5(ad)-15.6(h)11(e)-.6(ren)-15.6(c)9.8(e)]TJ
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[(bu)-15.9(t)-352.3(not)-362.7(in)-362.6(i)-15.9(n)10.6(divi)-15.9(d)10.6(u).3(al)-15.9(s)-352.1(w)-.6(ith)-362.6(p)-15.9(a)9.5(in)-362.6(al)-15.9(o)10.6(n).3(e.)-364.9(Howe)-15.9(v)9.5(e)-.9(r,)-364.9(the)-363.7(p)-15.9(r)10.7(e)-.9(se)-15.9(n)9.5(t)]TJ
T*
0 Tc
[(s)16.4(t)0(u)26.5(d)16.2(y)-306.4(w)0(a)24.6(s)-306.2(no)26.6(t)-306.5(p)16.2(ow)25.7(e)15(r)16.2(ed)-297.1(t)16.1(o)-312.1(d)16.2(e)15(t)16.1(e)15(ct)-297.2(t)16.1(h)16.2(is)-295.9(a)15(s)0(s)27(o)16.2(c)15(i)0(a)25.3(t)16.1(i)16.1(o)16.2(n,)-298.3(a)15(n)16.2(d)-306.4(d)0(i)26.5(d)-306.4(no)26.6(t)]TJ
T*
[(a)15(d)16.2(dr)26.6(e)15(s)0(s)-445.3(differences)-477.4(between)-478.7(individuals)-480.1(with)-472.1(and)-476.8(without)]TJ
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[(psychiatric)-459.3(illness/substance)-466.8(abuse.)-454.6(Therefore,)-461.4(the)-459.6(present)]TJ
0 -1.1116 TD
[(results)-239.1(are)-241.7(consistent)-238(with)-241.7(prior)-236(ndings.)-235.6(In)-238.3(analyses)-242.4(focused)]TJ
T*
[(on)-388.1(measures)-393.3(over)-391.4(time)-393(\(including)-392.7(repeated)-393.7(reports)-388.9(of)-388.1(pain)]TJ
0 -1.1174 TD
[()50.8(today,)45.2()-300.6(depression,)-304.5(and)-298.2(anxiety)-304(over)-299.3(the)-304.1(prior)-299.3(18)-301.7(months\))]TJ
0 -1.1116 TD
[(ndings)-278.2(were)-284(consistent)-278.3(with)-282(cross-sectional)-285.9(results,)-277.1(but)-279.9(did)]TJ
T*
[(not)-279.9(achieve)-283.2(statistical)-286.7(signicance.)]TJ
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[(This)-270.5(study)-270.4(offers)-272.4(initial)-274.5(evidence)-272.8(of)-272.9(the)-269.5(BCPQs)-274.1(potential)]TJ
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[(utility)-221.5(in)-221.2(identifying)-226.9(persons)-221.6(with)-224.4(chronic)-223.2(pain.)-222.2(Additionally,)]TJ
T*
[(its)-297.1(brevity)-297.1(makes)-296.9(it)-296.2(well)-300.4(suited)-295.8(for)-297(time-constrained)-300.2(clinical)]TJ
0 -1.1174 TD
[(and)-292.4(research)-289.7(settin)-8(gs.)-287.7(We)-287.9(suggest)-296.6(that)-288.1(the)-292.6(BCPQ)-289.4(may)-287.9(serve)]TJ
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[(as)-262.4(a)-261.4(simple)-268.3(and)-257.9(efcient)-265.8(method)-262.6(of)-261.4(preliminarily)-266.1(identifying)]TJ
T*
[(patients)-403(with)-403(chronic)-401.8(pain.)-400.8(Persons)-400(reporting)-402.9(at)-400.9(least)-399.6(mild)]TJ
T*
[(pain)-328.2(for)-325.8(greater)-328(than)-322.5(3)-329.4(months)-324.6(on)-324.7(the)-327.1(BCPQ)-324(would)-329.1(require)]TJ
0 -1.1174 TD
[(assessments)-424.9(of)-416.9(functional)-416.9(impairment)-419.3(using)-420.1(more)-415.7(detailed)]TJ
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[(instruments)-434.9(that)-432(assess)-428.6(pains)-433.9(impact)-430.9(\(e.g.,)-429.4(Brief)-434(Pain)-431.8(In-)]TJ
T*
[(ventory\))-246.2(and)-240.6(clinical)-243.2(assessments)-246.4(for)-245.1(common)-240.6(comorbidities)]TJ
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[(such)-281.8(as)-279.6(depression)-283.8(and)-280.9(anxie)-8(ty.)]TJ
1.0137 -1.1116 TD
[(This)-189.8(work)-189.6(has)-194.3(limitations.)-191.3(The)-190(sample)-194.4(reects)-195.2(a)-186.6(population)]TJ
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[(from)-264.7(a)-261.4(single,)-264.7(well-resourced)-268.6(HIV)-264.2(clinic)-262.7(in)-261.5(the)-263.8(Southeastern)]TJ
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[(Un)20(it)20.6(ed)-395(St)20.9(at)19.5(es)19.9(.)-406.6(T)0(h)19.6(e)0(s)19.9(e)-411.2(re)19.7(su)21(lt)26.3(s)-409.8(i)0(d)20.7(e)0(a)18.5(l)0(l)20.6(y)-410(sh)21(o)16.2(u)0(l)20.7(d)-410(be)-400.8(re)19.7(pl)20.7(i)16(c)0(a)18.5(t)0(e)19.6(d)-410(in)]TJ
0 -1.1116 TD
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T*
[(an)19.7(al)19.5(ys)21(es)-210.5(we)18.8(r)16.2(e)-226.9(a)15(d)0(e)19.7(q)0(u)20.8(a)0(t)19.5(e)0(l)19.5(y)-220(po)20.8(we)24.6(re)19.7(d)-220(\()]TJ
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[(42)20.8(\))-450.3(w)0(e)18.8(r)0(e)]TJ
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[(Al)19.8(th)20.7(ou)20.8(gh)-244.1(th)20.7(es)19.9(e)-249.9(l)0(i)20.6(m)0(i)19.5(t)0(a)19.6(t)0(i)14.8(o)0(n)20.8(s)-248.6(do)-244.1(ap)19.7(pl)20.7(y,)-240.7(th)20.7(e)-249.9(B)0(C)18.8(P)0(Q)-244.8(i)0(s)-238.3(s)0(t)20.9(r)0(e)19.7(n)0(g)15.1(t)0(h)20.7(-)]TJ
-1.0137 -1.1174 TD
[(en)19.7(ed)-337.4(by)-330.5(th)20.7(e)-347.8(d)0(e)19.7(c)0(a)18.5(d)0(e)19.7(s)0(-)21.1(l)0(o)20.7(n)0(g)-336.3(u)0(s)21(e)-347.8(of)-330.5(on)20.8(e)-347.8(o)0(f)-330.5(i)0(t)20.6(s)-346.5(tw)19.8(o)-340.9(q)0(u)15.1(e)0(s)19.9(t)0(i)20.6(o)0(n)20.8(s)-346.5(in)]TJ
0 -1.1116 TD
-.0194 Tc
[(t)-19.4(h)1.3(e)-361.5(S)-19.4(F-)-19.4(8)-349.9(\()-19.4()53.3()-19.4(Ho)-19.4(w)-350.8(m)-19.4(uc)-19.4(h)-345.3(b)-19.4(od)-19.4(il)-19.4(y)-344.3(p)-19.4(ai)-19.4(n)-350(h)-19.4(av)-19.4(e)-345.3(y)-19.4(ou)-354.6(h)-19.4(a).3(d)-360.3(d)-19.4(ur)-19.4(in)-19.4(g)-349.9(t)-19.4(he)]TJ
T*
0 Tc
[(la)19.5(st)-434.1(we)18.8(ek)19.7(?)71.5(\))-434.1(an)19.7(d)-444.6(b)0(y)-428.4(t)0(h)20.7(e)-445.8(pr)20.9(ec)18.5(ed)19.7(in)20.7(g)-444.6(s)0(t)20.9(u)0(d)20.8(y)-444.6(in)-428.5(2,)18.5(00)20.8(0)-438.8(h)0(e)19.7(a)0(l)13.8(t)0(h)20.7(y)]TJ
0 -1.1174 TD
[(No)20(rw)20(eg)19.7(ia)13.8(ns)21(.)]TJ
7.3823 0 0 6.5614 110.948 247.3511 Tm
(11)Tj
9.843 0 0 9.843 122.4 242.929 Tm
[(It)20.7(s)-415.6(p)0(a)19.7(r)0(t)20.7(i)0(c)13.8(i)0(p)20.7(a)0(n)19.7(t)-415.9(bu)20.8(rd)20.9(en)-412.3(is)-405.3(ex)19.7(tr)20.7(em)18.5(el)19.5(y)-421.6(l)0(o)20.7(w)0(,)-408.6(a)0(n)19.7(d)]TJ
-6.1341 -1.1116 TD
[(pr)20.9(io)20.7(r)-375.4(q)0(u)20.8(a)0(l)19.5(i)0(t)20.6(a)0(t)13.8(i)0(v)20.7(e)-370.9(wo)20(rk)-365(fo)20.9(un)20.8(d)-375.5(t)0(h)20.7(a)0(t)-366.4(i)0(t)-359.6(w)0(a)13(s)-369.5(un)20.8(de)19.7(rs)15.3(ta)19.6(nd)20.8(ab)19.7(le)-366.4(an)19.7(d)]TJ
T*
[(ac)18.5(ce)18.5(pt)20.7(ab)19.7(le)-400.9(to)-399.7(in)15(di)20.7(vi)20.7(du)20.8(al)19.5(s)-409.8(w)0(i)19.8(t)0(h)-399.7(H)0(I)14.2(V)0(.)]TJ
7.3823 0 0 6.5614 206.3055 225.411 Tm
(13)Tj
9.843 0 0 9.843 217.644 221.0456 Tm
[(As)-400.3(pr)20.9(ev)19.7(io)15(us)21(ly)-399.7(no)20.8(te)19.6(d,)]TJ
-15.8104 -1.1174 TD
[(in)20.7(st)15.1(ru)20.9(me)18.4(nt)20.7(s)-536.6(s)0(u)21(c)0(h)-527.5(a)0(s)-533.1(t)0(h)20.7(e)-537.9(SF)21.2(-3)20.9(6)-536.7(o)0(f)20.9(t)0(e)13.8(n)-536.7(un)20.8(de)19.7(rg)20.9(o)-536.7(d)0(e)19.7(c)0(a)18.5(d)0(e)19.7(s)-542.3(of)]TJ
0 -1.1116 TD
[(va)19.7(li)20.6(di)15(ty)-388.2(te)13.8(st)20.9(in)20.7(g)-404.3(b)0(u)20.8(t)-404.4(ar)19.7(e)-405.4(o)0(f)20.9(t)0(e)19.6(n)-404.3(us)21(ed)-395(fo)20.9(r)-404.2(r)0(e)19.7(s)0(e)19.9(a)0(r)14(c)0(h)-389.3(a)0(n)19.7(d)-404.3(cl)19.5(in)15(ic)19.6(al)]TJ
T*
[(pu)20.8(rp)20.9(os)15.3(es)-389.1(du)20.8(ri)20.7(ng)-393.9(th)20.7(at)-389.4(pr)20.9(oc)19.7(es)19.9(s.)-390.2(Th)19.6(er)19.7(ef)14(or)20.9(e,)-391.6(th)20.7(es)19.9(e)-399.7(d)0(a)19.7(t)0(a)-389.4(p)0(r)15.1(o)0(v)20.8(i)0(d)20.7(e)]TJ
T*
[(su)21(pp)20.8(or)15.1(t)-260.4(f)0(o)20.9(r)-260.3(HI)20(V)-261.1(c)0(l)19.5(i)0(n)20.7(i)0(c)19.6(i)0(a)19.6(n)0(s)-249.7(a)0(n)13.9(d)-254.5(re)14(se)19.9(ar)19.7(ch)19.7(er)19.7(s)-260.1(w)0(h)20(o)-260.3(wi)19.8(sh)-255.4(to)-250(be)19.7(gi)20.7(n)]TJ
0 -1.1174 TD
[(us)21(in)20.7(g)-317.9(t)0(h)20.7(e)-319(BC)18.8(PQ)20.1(.)-314.5(F)0(u)21(t)0(u)20.7(r)0(e)-308.6(s)0(t)20.9(u)0(d)15.1(i)0(e)19.6(s)-311.9(us)15.3(in)20.7(g)-312.1(t)0(h)20.7(e)-319(BC)18.8(PQ)-308.2(wi)19.8(ll)-307.7(en)19.7(ab)19.7(le)]TJ
0 -1.1116 TD
[(in)20.7(ve)19.7(st)15.1(ig)20.7(at)19.5(io)20.7(n)-289.1(o)0(f)-284.4(c)0(h)19.7(r)0(o)20.9(n)0(i)20.7(c)-290.2(pa)19.7(in)20.7(s)-284.2(pr)20.9(ev)19.7(al)19.5(en)19.7(ce)-286.7(am)18.5(on)20.8(g)-289.1(i)0(n)20.7(d)0(i)20.7(v)0(i)20.7(d)0(u)15.1(a)0(l)19.5(s)]TJ
T*
[(wi)19.8(th)-261.5(HI)20(V)-266.9(a)0(n)19.7(d)-271.8(th)20.7(e)-267.2(r)0(e)19.7(l)0(a)19.5(t)0(i)20.6(o)0(n)15.1(s)0(h)21(i)0(p)-255.8(b)0(e)19.7(t)0(w)14.1(e)0(e)18.5(n)-266(ch)19.7(ro)20.9(ni)20.7(c)-273(p)0(a)19.7(i)0(n)-255.8(a)0(n)19.7(d)-271.8(HI)20(V)]TJ
0 -1.1174 TD
[(be)19.7(ha)19.7(vi)20.7(or)15.1(al)-256.9(an)19.7(d)-271.8(c)0(l)19.5(i)0(n)20.7(i)0(c)13.8(a)0(l)-256.9(o)0(u)20.8(t)0(c)19.6(o)0(m)19.6(e)0(s)14.1(.)]TJ
/F1 1 Tf
8.9663 0 0 8.9663 62.022 105.959 Tm
(Acknowledgments)Tj
/F4 1 Tf
9.843 0 0 9.843 72 89.5181 Tm
[(This)-218.6(research)-220.6(was)-218.3(supported)-218.3(by)-221.1(the)-217.7(University)-220.6(of)-215.3(Alabama)]TJ
-1.0137 -1.1116 TD
[(at)-262.7(Birmingham)-257.8(\(UAB\))-261.7(Center)-263.5(for)-262.4(AIDS)-259.4(Research)-261.9(CFAR,)-264.1(an)]TJ
0 -1.1174 TD
[(NIH)-287.2(funded)-284.2(program)-292.3(\(P30)-280.7(A1027767\))-287.2(that)-288(was)-287.4(made)-284.4(possi-)]TJ
0 -1.1116 TD
[(ble)-246.5(b)16.2(y)-231.5(th)26.5(e)-232.6(f)16.2(o)16.2(l)16.1(lo)26.5(w)15.3(i)16.1(ng)-215.3(in)26.5(s)16.4(t)0(i)26.3(t)16.1(u)16.2(t)16.1(es)25.6(:)-231.6(N)15.3(I)16.2(A)0(I)25.8(D)15.3(,)-233.8(N)15.3(C)15.2(I)16.2(,)-233.8(N)15.3(I)16.2(C)15.2(HD)24.9(,)-228.1(N)15.3(HL)24.5(B)15.2(I)16.2(,)]TJ
25.504 67.9184 TD
[(NIDA,)-482.7(NIMH,)-482.8(NIA,)-480.7(FIC,)-479.9(and)-482.5(OAR.)-481.8(J.S.M.)-480.7(is)-474.4(supported)]TJ
0 -1.1174 TD
.0188 Tc
[(b)-5.3(y)-494.9(1)-5.3(K)-.4(12)-5.3(HS0)-5.3(216)-5.3(940)-5.3(1)-494.9(\()-5.3(AHR)-6.4(Q\).)-503(C)-.6(.S.R.)-497.2(i)-5.5(s)-494.7(s)-5.1(up)-5.3(por)-5.3(ted)-500.7(b).4(y)]TJ
0 -1.1116 TD
.0186 Tc
[(7)-5.5(K)-.6(07)-5.5(AG0)-5.5(317)-5.5(79)-253.2(\()-5.5(N)-.6(IA)-6.4(\).)-255.5(Fun)-5.5(d).2(in)-5.5(g)-253.2(w)-.6(as)-258.8(als)-5.3(o)-253.2(pro)-5.5(v).2(id)-5.5(ed)-253.2(by)-259(the)]TJ
T*
.0197 Tc
[(M)-5.3(a).2(ry)-280.9(Fisher)-280.9(CA)-5.3(RE)-282.1(Fund)-280.9(at)-281(U)-5.3(A).5(B.)]TJ
/F1 1 Tf
8.9663 0 0 8.9663 313.0582 667.9557 Tm
0 Tc
[(Author)-338.7(Disclosure)-336.7(Statement)]TJ
/F4 1 Tf
9.843 0 0 9.843 323.0361 651.5148 Tm
[(No)-279.5(competing)-284.4(nancial)-283.1(interests)-288.7(exist.)]TJ
/F1 1 Tf
8.9663 0 0 8.9663 313.0582 627.1368 Tm
(References)Tj
/F4 1 Tf
9.2951 0 0 9.2951 317.707 611.0361 Tm
[(1.)-500.4(In)15.7(s)12.9(t)12.6(it)19.2(ut)18.6(e)-199.5(o)0(f)-197.8(M)12.8(ed)19.9(i)12.6(c)0(i)14.4(n)0(e)26(:)]TJ
/F6 1 Tf
9.8808 0 TD
[(Re)18(l)12.6(i)12.6(e)0(v)15.7(i)12.6(ng)-195.5(Pa)22.2(i)12.6(n)-207.5(i)12.6(n)-207.5(Am)20.6(e)14(r)0(i)19.5(c)0(a)19.9(:)-203.7(A)-203.3(B)0(l)16.7(u)0(e)19.9(p)0(r)25(i)0(n)18.6(t)]TJ
-8.6304 -1.1223 TD
[(fo)18.6(r)-176.1(T)0(r)22.1(a)0(n)24.1(s)0(f)19.5(o)0(r)18.9(m)0(i)23.1(n)0(g)-165(P)0(r)17(e)14(ve)15.7(nt)24.7(io)18.6(n,)-164.9(C)13.4(a)0(r)18.9(e)0(,)-163(E)0(d)16.1(u)0(c)26(a)0(t)18.6(i)12.6(on)18(,)-177(a)0(n)24.1(d)-177(Re)24.1(se)20.8(ar)18.9(ch)]TJ
/F4 1 Tf
23.726 0 TD
(.)Tj
-23.726 -1.1284 TD
[(Th)16.1(e)-266.6(N)0(a)18.3(t)12.6(io)18.6(na)19.9(l)-267.9(A)0(c)18.3(a)13.9(de)19.9(mi)19(es)-259.8(Pr)18.9(e)14(s)0(s)19.8(,)-268.4(Wa)15.6(s)12.9(h)0(i)18.6(n)0(g)24.1(t)0(o)18.6(n)0(,)-256.4(D)0(C)17.8(,)-268.4(20)24.1(11)18(.)]TJ
-1.2503 -1.1223 TD
[(2.)-500.4(Pe)17(rr)19.5(y)-286.8(B)13.4(A,)-276.3(We)15.6(s)12.9(t)12.6(fa)17.6(l)12.6(l)-286.2(AO)14.9(,)-280.6(M)0(o)18.8(l)12.6(on)18(y)-286.8(E)0(,)]TJ
/F6 1 Tf
15.675 0 TD
[(et)-278.4(al)24.7(.:)]TJ
/F4 1 Tf
2.6227 0 TD
[(Ch)19.3(ar)23.7(ac)15.7(t)12.6(e)0(r)17.6(i)12.6(st)19.5(i)12.6(c)0(s)-278.1(o)0(f)]TJ
-17.0474 -1.1284 TD
[(an)-193.6(am)20.3(bu)18(l)12.6(a)0(t)20.5(o)0(r)21.8(y)-201.4(pa)19.9(ll)19.2(i)12.6(a)0(t)20.5(i)0(v)18.6(e)-199.5(ca)15.7(re)-189.8(cl)20.5(in)18.6(i)12.6(c)-205.6(fo)21.8(r)-203.7(H)0(I)20.2(V)0(-)20.2(i)12.6(nf)21.8(ec)15.7(t)12.6(e)0(d)-193.6(p)0(a)19.9(t)12.6(i)12.6(e)0(n)19.9(t)0(s)19.5(.)]TJ
0 -1.1223 TD
[(J)-273.7(P)15.3(al)14.4(l)12.6(i)12.6(a)0(t)-260.1(M)0(e)20.6(d)-268.5(20)18(13)24.1(;1)18.6(6\()21.8(8\))21.8(:)12.6(9)0(3)18(4)0()24.1(9)0(3)18(7)0(.)]TJ
-1.2503 -1.1284 TD
[(3.)-500.4(Merlin)-328.8(JS,)-319.5(Westfall)-324.7(AO,)-320.7(Raper)-327.3(JL,)]TJ
/F6 1 Tf
15.8397 0 TD
[(et)-321.1(al.:)]TJ
/F4 1 Tf
2.7325 0 TD
[(Pain,)-324.3(mood,)-323.5(and)]TJ
-17.3218 -1.1223 TD
[(substance)-365.3(abuse)-355.9(in)-353.5(HIV:)-359.2(Implications)-362.6(for)-352.7(clinic)-361.3(visit)-358(utili-)]TJ
0 -1.1284 TD
[(zation,)-551(ART)-551.5(adherence,)-549.3(and)-547.5(virologic)-548.9(failure.)-549.7(J)-548.2(Acquir)]TJ
0 -1.1223 TD
[(Immune)-335.9(Dec)-336.7(Syndr)-335.3(2012;61\(2\):164170.)]TJ
-1.2503 -1.1284 TD
[(4.)-500.4(Merlin)-438.5(JS,)-429.3(Westfall)-434.5(AO,)-436.6(Chamot)-429.7(E,)]TJ
/F6 1 Tf
16.8949 0 TD
[(et)-430.9(al.:)]TJ
/F4 1 Tf
2.9581 0 TD
[(Pain)-434.1(is)-431.9(inde-)]TJ
-18.6027 -1.1223 TD
[(pendently)-514.8(associated)-515.5(with)-513.3(impaired)-516.6(physical)-513.8(function)-512.8(in)]TJ
0 -1.1284 TD
[(HIV-infected)-340.5(patients.)-336.4(Pain)-336.5(Med)-333.3(2013;14\(12\):19851993.)]TJ
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[(5.)-500.4(R)-11(u)-12.3(t)-11.8(j)0(e)-16.1(s)-481.1(A)-7.8(W)-16.7(,)-475.8(R)-11(e)-10.4(i)-11.8(ts)-17.1(m)-11.9(a)-480.1(JB)-16.4(,)-481.9(C)-11(o)-6.2(o)-12.3(m)-11.9(a)-10.4(r)-8.6(a)-10.4(s)-11.4(a)-10.4(m)-11.9(y)-475.9(A)-7.8(,)]TJ
/F6 1 Tf
20.2129 0 TD
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[(et)-465.7(al.:)]TJ
/F4 1 Tf
3.0862 0 TD
.0123 Tc
[(Ev)6.1(a-)]TJ
-22.0487 -1.1284 TD
.0112 Tc
[(luati)11.2(o)-6.8(n)-293.9(o)-1.1(f)-296.2(d)-1.1(iag)5(n)-1.1(o)5(s)-.3(tic)-298.1(t)11.2(e)-11(s)11.2(t)-5.9(s)-299.1(w)3.4(hen)-293.9(t)-.6(here)-298.1(is)-299.1(n)5(o)-300(g)5(o)-1.1(ld)-293.9(stan)5(dard.)]TJ
0 -1.1223 TD
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[(A)-240.1(r)3.1(eview)-234(o)-.6(f)-240.8(m)11.7(etho)5.5(ds.)-238.4(H)3.9(ealth)-232.4(Techn)5.5(o)-.6(l)-237.9(A)3.9(ssess)-237.6(2)5.5(007)5.5(;11)5.5(\()3.1(50\):)]TJ
0 -1.1284 TD
.012 Tc
[(iii,)-329.6(ix)5.8(5)5.8(1.)]TJ
-1.2503 -1.1284 TD
0 Tc
[(6.)-500.4(Davis)-450.3(KD,)-454.9(Racine)-450.7(E,)-447.3(and)-449.9(Collett)-452.9(B:)-449.7(Neuroethical)-453.8(issues)]TJ
1.2503 -1.1223 TD
[(related)-313.7(to)-304.7(the)-302.9(use)-308.7(of)-307.6(brain)-305.5(imaging:)-308.2(Can)-308.3(we)-304.9(and)-303.5(should)-310.5(we)]TJ
0 -1.1284 TD
[(use)-266(brain)-262.8(imaging)-259.8(as)-265.9(a)-260.5(biomarker)-263.4(to)-262(diagnose)-264.3(chronic)-261.2(pain?)]TJ
0 -1.1223 TD
[(Pain)-336.5(2012;153\(8\):15551559.)]TJ
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[(7.)-500.4(Borsook)-354.9(D,)-355.5(Becerra)-362.7(L,)-349.8(and)-358.4(Hargreaves)-359.1(R:)-352.2(Biomarkers)-359(for)]TJ
1.2503 -1.1223 TD
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[(ch)-15.5(r)12.4(o)-15.5(n)14.7(i)-2.9(c)-306.5(p)2.7(ain)-308.4(a)-1.5(nd)-308.4(analg)-15.5(e)10.5(sia.)-308.3(Part)-307.8(2:)-307.8(Ho)-15.5(w)13.1(,)-308.3(wh)-15.5(e)10.5(r).3(e,)-308.3(and)-308.4(w)1.1(h)-15.5(a)10.5(t)-301.7(t)-2.9(o)]TJ
0 -1.1284 TD
0 Tc
[(l)12.6(o)0(o)30.2(k)-286.8(f)15.8(o)18.2(r)-289.1(u)18.2(s)12.9(i)12.6(n)18.2(g)-286.8(f)15.8(u)0(n)30.2(c)14(t)12.6(i)18.7(on)30.2(a)13.9(l)-286.2(i)12.6(m)12.5(a)14(g)18.2(i)12.6(n)18.2(g.)-268.6(Di)29.2(s)12.9(c)14(ov)-268.7(M)12.8(e)14(d)-286.8(2)18.2(01)30.2(1;)30.8(11)30.2(\(5)27.9(8\))27.9(:)]TJ
0 -1.1223 TD
[(20)30.2(9)30.2(21)24.1(9)18.2(.)]TJ
-1.2503 -1.1284 TD
[(8.)-500.4(Marchi)-364(A,)-355.5(Vellucci)-367.4(R,)-358.8(Mameli)-360.7(S,)]TJ
/F6 1 Tf
15.5164 0 TD
[(et)-357.7(al.:)]TJ
/F4 1 Tf
2.8117 0 TD
[(Pain)-360.9(biomarkers.)]TJ
-17.0779 -1.1223 TD
[(Clin)-339.7(Drug)-333.8(Investig)-335(2009;29\(Suppl)-329.2(1\):4146.)]TJ
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[(9.)-500.4(Vervest)-371.7(AC)-360.4(and)-364.5(Schimmel)-364.2(GH:)-369(Taxonomy)-360.6(of)-362.5(pain)-364.1(of)-362.5(the)]TJ
1.2503 -1.1223 TD
[(IASP.)-339.7(Pain)-330.4(1988;34\(3\):318321.)]TJ
-1.7505 -1.1284 TD
[(10.)-500.5(Am)16.9(e)14(r)0(i)16.3(c)13.9(an)-224.1(Ps)22.1(yc)19.9(hi)18.6(a)13.9(t)0(r)16.3(i)12.6(c)-230(A)0(s)17.3(s)12.9(oc)19.9(i)12.6(a)0(t)20.5(i)0(o)18.6(n)0(:)]TJ
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